New Spectra/Por® Tube-A-Lyzer® Disposable & Ready-to-Use Dynamic-Dialysis Device
Spectrum's Tube-A-Lyzer is a ready-to-use, gentle separation device that combines convenience and disposability
with the efficiency of dynamic dialysis to significantly increase the mass transfer rate and reduce the overall
dialysis from 1-2 days to 4-8 hours. This self-contained, disposable device incorporates a semi-permeable
membrane tubing that separates the sample chamber from the surrounding flow-through buffer chamber.
The dry Biotech Grade Cellulose Ester (CE) membrane tubing is available in 6 MWCO's and the
membrane-defined sample chamber is available in 2 volume sizes. The sample port provides easy access for
loading, recovering and in-process testing. The housing is designed to be a flow-through dialysate chamber
that can be connected to a buffer source and a waste collection vessel, or for discharging directly to drain.
Tube-A-Lyzer is non-pyrogenic and can be sterilized (25 kGy gamma irradiation).
Mounted onto the support rack of the KrosFlo® Research II Pump System; Spectrum Laboratories part
no. ACR2-021-01N (110V) or ACR2-022-01N (220V), the Tube-A-Lyzer device can be operated as a single unit or in
parallel when multiple units are combined using a coupling bracket (sold separately) into a multi-unit device.
A second pump head can be mounted to the pump to operate two Tube-A-Lyzer units in parallel.
ADVANTAGES OF DYNAMIC DIALYSIS
Faster dialysis; reduced from 1-2 days to 4-12 hrs
Ready-to-Use and disposable: no preparation required
Easy sample loading, in-process testing and recovery
2 Volume sizes (8-10 ml & 25-30 ml) Biotech Grade Cellulose Ester (CE) Membrane
Polycarbonate top and bottom piece Polyurethane potting Female Luer-lok sample port Polypropylene male Luer-lok cap
Buffer Chamber
Polycarbonate housing Polycarbonate end caps 5 mm (3/16 inch) hose-barb inlet / outlet ports
Dynamic Pump Rate
10-20 ml/min (should be optimized for application)
